Research Interests:
Our research activities are mainly in the areas of nucleic acid biochemistry, protein biochemistry, peptide/protein chemistry, bioanalytical chemistry, chemical biology, and bioengineering. Our research aim is to develop a next-generation platform for disease diagnostics and therapy. To realize this aim, we are interested in playing with Nature's building blocks, peptide, protein, DNA and RNA.
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Topics of interest:
Fluorescent sensors, protein-binding ligand, drug delivery
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Currently, my laboratory is pursuing projects focused on the design of fluorescent sensors and drug precursors targeting proteins of biomedical importance. Two major research directions include:
Developing probes and inhibitors for the CoV spike proteins, aimed at understanding viral entry mechanisms and identifying potential antiviral strategies.
Engineering aptamers and peptides that target human immune checkpoint proteins (PD-1, PD-L1, PD-L2), with the long-term goal of creating novel modulators for immunotherapy.
Together, these efforts advance the discovery of next-generation peptide and nucleic acid probes for molecular recognition, with applications in disease diagnostics, therapeutics, and fundamental biochemical research.