Research Interests:
Our research activities are mainly in the areas of nucleic acid biochemistry, protein biochemistry, peptide/protein chemistry, bioanalytical chemistry, chemical biology, and bioengineering. Our research aim is to develop next-generation platform for disease diagnostics and therapy. To realize this aim, we are interested in playing with Nature's building blocks, peptide, protein, DNA and RNA.
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Topics of interest:
Fluorescent hairpins, peptide/protein chemistry, aptamer, antibody delivery, antibody mimics
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Current Project:
1. PD-L1/PD-1 interaction
PD-L1 are constitutively expressed or overexpressed on different types of human tumor cells.
Since cancer cells use the PD-L1 to help them evade immune attack, inhibitors that target PD-L1 can block this binding and boost the immune response against cancer cells. Our group is interested in developing biosensors for PD-L1 detection.
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2. COVID-19
We recently received a NSF grant in this project and look for a post doc now!
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